How Much Vitamin B12 Should I Take?
If you are wondering what the right amount of vitamin B12 to take is, you have come to the right place. Here, you will learn about the common forms of this vitamin and the health risks associated with taking too much of it. Also, you will discover what the symptoms of a deficiency in B12 are and what you can do to prevent it.
Symptoms of a vitamin B12 deficiency
If you experience any of the following symptoms, you may have a vitamin B12 deficiency. Symptoms can range from mild to severe and can be caused by several factors. You should always seek medical attention if you suspect that you are experiencing these symptoms. Some symptoms can go unnoticed and if left untreated, can cause irreversible damage.
Vitamin B12 is needed for healthy nerve function. Without the appropriate amount of the nutrient, you can develop a range of neurological problems. This condition can affect the central nervous system, peripheral nerves and the spinal cord. The symptoms of a B12 deficiency can range from depression and fatigue to memory loss and anemia.
Deficiency can occur in both men and women, though it is most common in older adults. There are a number of causes for this problem, including dietary deficiencies, gastrointestinal disease, certain medications and an autoimmune disorder.
Symptoms can be quite varied, and can start gradually and then progress quickly. For example, a person with a mild deficiency may only have a headache and pale hands. However, a person with a more severe deficiency may have symptoms such as weakness, fatigue, difficulty breathing, confusion, and deep depression.
Although it is not uncommon to be deficient in vitamin B12, it is important to know what signs to look for. Your doctor can perform blood tests to determine if you are experiencing a deficiency. They can also check to see if you are suffering from a condition such as pernicious anemia.
Taking a test to determine if you are deficient in B12 can help to determine what kind of treatment will work best for you. Typically, regular injections of 1000 micrograms of vitamin B12 are given for 4-6 weeks. These injections allow the body to produce red blood cells.
Vitamin B12 is found in meat, fish, dairy products and yeast extract. It can also be taken as a supplement. People who are vegetarian or vegan should make sure to include fortified versions of this vitamin in their diet.
Medications that can prevent the body from absorbing B12 are proton pump inhibitors, anticonvulsants and certain anti-ulcer drugs. In addition, a person who takes a drug for diabetes may have lower absorption of this nutrient.
Common forms of vitamin B12 in supplements
When considering taking vitamin B12 supplements, it is important to understand the different forms of this vitamin. Some forms are more bioactive and some are less so. It is also important to find out whether your body will absorb the form you are taking.
One of the more common forms of B12 in supplements is cyanocobalamin. This form is relatively stable, but requires a lot of conversion before it becomes usable in the human body.
Another common form of B12 in supplements is adenosylcobalamin. Adenosylcobalamin is a mitochondrial coenzyme, which means it only works in the mitochondria. In addition to promoting DNA synthesis, it is essential to amino acid metabolism and red blood cell formation. However, it is not produced naturally in the human body.
Cyanocobalamin is a synthetic form of B12. It is manufactured and distributed as a supplement. The active ingredient in most oral supplements is cyanocobalamin.
The best way to ensure that your vitamin B12 levels stay high is to take the right types of supplements. There are four different forms of B12: methylcobalamin, adenosylcobalamin, hydroxycobalamin, and cyanocobalamin. Whether your body absorbs the forms you are taking may depend on your age, health, diet, and genetics. If you are concerned about your intake of B12, contact a health care provider for more information.
Vitamin B12 is available in a number of food products, including cheese, eggs, and meat. However, vegans and vegetarians are at an increased risk of deficiency, and may need to take supplements.
People who have a gene mutation for COMT, a protein involved in converting cyanocobalamin to a usable form of B12, should avoid taking the methylcobalamin form of the vitamin. As an alternative, ask your health care provider what type of hydroxocobalamin is best for you.
Injections are another common way to get vitamin B12. They are especially effective at raising blood levels, and are not as expensive as oral supplements. Unfortunately, they are not as effective at absorption as other methods.
Vitamin B12 deficiency can lead to a number of problems. These include fatigue, lightheadedness, neurological damage, and abnormal sensations.
Increased cancer risk
A number of studies have shown that having elevated plasma vitamin B12 levels is associated with an increased risk of certain cancers. However, the actual link between these two factors remains elusive.
Among the studies, a handful of large scale data sets have provided an answer to this question, and the results have been mixed. In this meta-analysis, we examined the various strengths and weaknesses of these data sets, to determine the magnitude of the association between elevated B12 levels and cancer.
The largest increase in risk was seen among individuals with lung cancer. Although this was the only type of cancer for which a significant association was observed, the number of cases was still relatively small. Furthermore, the association between elevated plasma B12 and lung cancer lasted for a long time. Similarly, studies that investigated the link between high plasma B12 and liver cancer found that the effect persisted for at least five years after the initial measurement.
One study reported that the association between high plasma B12 and cancer was statistically significant. Another found that people with a genetic variation called the MTR A2756G polymorphism had a lower risk of developing leukemia. Nevertheless, these studies were more than a decade old. Therefore, the true value of the MTR A2756G polymorphism for cancer risk may still be unknown.
One of the most intriguing findings was that elevated plasma B12 was not associated with an increased risk of prostate cancer. Interestingly, these findings were not replicated in a secondary cohort. Moreover, the association between high plasma B12 and prostate cancer was not statistically significant, and the study did not address the potential confounders of smoking or alcohol consumption. Despite the lack of statistical significance, it is nonetheless worth noting that elevated plasma B12 is prevalent.
Finally, a few studies investigated whether taking a high-dose B6/B12 supplement could reduce the risk of cancer. While these studies did not provide a definitive conclusion, they were able to demonstrate that the use of these supplements can reduce the risk of several cancers. This suggests that these compounds are more easily absorbed and thus have some sort of cancer-reducing effect.
Side effects of too much vitamin B12
Too much vitamin B12 can have a number of negative side effects. Specifically, it can cause problems with the gastrointestinal system and the skin. In addition, it can also cause allergic reactions.
Vitamin B is a water-soluble vitamin that helps with DNA synthesis and the health of red blood cells. It is found in food products fortified with the vitamin. This type of vitamin is particularly important for pregnant women and those who are breastfeeding. However, it is not advisable to take excessive amounts.
If you are pregnant or breastfeeding, you should not take more than 2.8 micrograms of B-12 per day. Pregnant women and breast-feeding women should consult with their healthcare provider before taking any dietary supplements.
Some studies show that higher levels of vitamin B12 can increase the risk of lung cancer in men. Other studies suggest that high levels of the vitamin can increase the risk of heart attacks.
A recent study of over a million people found that people with high vitamin B12 levels were more likely to die from lung cancer than those with low levels. Despite these findings, there is no definitive evidence that excess B12 causes these conditions.
Taking too much of the vitamin can also lead to anemia, a condition that causes too many red blood cells. This can lead to fatigue and depression. Anemia can be caused by other conditions, such as gastrointestinal issues, liver disease, kidney disorders, or diabetes.
Many people take dietary supplements for a number of reasons, including to improve endurance and energy. While most of these supplements are safe, some have side effects. These include rosacea, acne, and GI tract complications.
There is no recommended maximum daily dosage of B12. Taking more than this can have a range of negative side effects. Those with gastrointestinal problems or prescription medications should talk with their doctor before starting new dietary supplements.
It is possible to take vitamin B12 in megadoses. Several research studies have shown that these high doses are safe, but they can lead to a number of side effects.