Ellagic Acid Benefits
Ellagic acid benefits include protection from ultraviolet radiation, antioxidant effect, anti-inflammatory properties and inhibition of reactive chemical carcinogens. Also, this compound may slow the expansion of adipocytes, reducing the risk of cardiovascular diseases. It also has the ability to protect the skin from sunburn.
Anti-inflammatory properties
Ellagic acid is a powerful antioxidant that is found in many fruits and vegetables. It has antiviral and antibacterial properties, as well as an anti-inflammatory action.
Ellagic acid has been shown to protect the pancreatic stellate cells from reactive oxygen species. In addition, it has a protective effect against chronic pancreatitis. This is because it inhibits the production of inflammatory cytokines like IL-1.
As a result, it has been used in treating various diseases, such as heart disease and cancer. In fact, a recent study has showed that ellagic acid could reduce the risk of developing prostate cancer in men. Interestingly, it also reduced the side effects of chemotherapy in men with advanced prostate cancer.
Ellagic acid is a natural polyphenol that can be found in various fruits and vegetables. It is particularly prevalent in berries. However, it is also found in walnuts, pecans, and oak.
The anti-inflammatory properties of ellagic acid have been investigated in several animal models. In one study, a topical application of ellagic acid was able to prevent collagen breakdown in hairless mice. Moreover, it was able to protect the skin from the harmful effects of UV light exposure.
Another study conducted by Corbett et al. (2010) examined the anti-inflammatory properties of ellagic acids in animal models. They found that ellagic acid significantly decreased the total hepatic mucosal cytochromes, and attenuated the damage caused by H2O2 in the liver. Moreover, it was also able to reduce the production of pro-inflammatory cytokines like TNF-a and IL-1.
Anti-cancer properties
Ellagic acid is a naturally occurring compound found in a variety of fruits and vegetables. It is an organic heterotetracyclic molecule that crystallizes from Ac2O. Various studies have shown that ellagic acid has antioxidant and anti-cancer properties.
Ellagic acid has been shown to inhibit cancer in several in-vivo models. However, more research is needed to evaluate the anti-cancer properties of ellagic acid.
Ellagic acid inhibits the growth of tumors in mice. In addition, it decreases inflammation. These effects may be due to the chemical’s ability to bind with cancer-causing molecules.
Ellagic acid reduces cell death in human osteogenic sarcoma. Additionally, it enhances detoxification of reactive intermediates. The cytotoxic effects of ellagic acid are thought to be caused by inhibition of oxidative stress and by apoptosis.
While more research is needed, preliminary studies suggest that ellagic acid may inhibit the growth of many types of cancers. Currently, there are no known clinical trials using ellagic acid for treatment of cancer.
Although most of the research on ellagic acid has been conducted on animals, there are some promising results. A study on rat mucosa found that dietary ellagic acid decreased total hepatic mucosal cytochromes. Also, a Brazilian study showed that ellagic acid was detected in exotic fruits.
Currently, the majority of the American population is obese, which increases their risk of diabetes and heart disease. Adding more fruits and vegetables to the diet can reduce the risk of these diseases.
Protects skin from sunburn
Ellagic acid is a substance found in pomegranates, nuts, and vegetables that is found to protect the skin from the sun. Its antioxidant properties can help to prevent wrinkles, prevent damage from UVA and UVB rays, and protect the skin against inflammation.
Ellagic acid is also known to inhibit the matrix metalloproteinase enzyme, which is known to damage collagen. The enzyme breaks down natural collagen in the skin. Ellagic acid works to block the production of the enzyme, thereby protecting the skin from the effects of UVA and UVB rays.
A recent study has shown that pomegranate juice, which contains high levels of ellagic acid, can protect the skin from the sun. Researchers from the Hallym University in the Republic of Korea conducted the research. In the experiment, twelve hairless mice were exposed to increasing amounts of ultraviolet radiation.
Results showed that ellagic acid protected the mice from sunburn. Compared to control mice, the mice that were treated with the pomegranate extract had a 20% increase in the Sun Protection Factor.
Another study, conducted by the researchers, showed that the polyvalent metal salt of ellagic acid derivative was insoluble in water, fats, oils, and alcohol. This compound can be combined with other additives and used in skin care preparations.
Ellagic acid is one of several substances that can reduce the intensity of sunburn. Vitamin E and vitamin C are also known to protect the skin from UV rays. Lycopene, an antioxidant found in tomatoes and red grapes, can also be beneficial for the skin.
May inhibit reactive chemical carcinogens
Ellagic acid is a polyphenolic compound that is found in a variety of fruits and vegetables. It is also present in some medicinal plants. Several studies have been conducted to understand the role of ellagic acid as an anticarcinogen. Some of these studies have been conducted for dietary intake, while others have been conducted for its ability to affect organ accumulation in animal systems.
Ellagic acid is produced by the hydrolysis of ellagitannins. The ellagitannins in pomegranate, for example, contain relatively high amounts of ellagic acid. This has prompted researchers to explore the potential use of ellagic acid in fruit juice processing, as well as in the wine industry.
Ellagic acid has been shown to inhibit the growth of Salmonella typhimunium and to decrease the presence of potentially mutagenic chemicals. Researchers have also reported that ellagic acid has beneficial effects on alcoholic liver disease. In addition, it has been reported to have antifibrotic effects.
Ellagic acid can bind to reactive metabolic forms of carcinogens. This reactivity may enhance oxidative stress in cancer cells. A study involving DMBA and ellagic acid revealed that ellagic acid inhibited DMBA’s ability to activate the DNA-binding domains of the cytochrome P450 enzymes. Also, ellagic acid inhibited a methylation event at the quanine position of the pyrene ring.
Ellagic acid possesses an ability to reduce IL-1b and TNF-a serum levels, and ameliorate lipid peroxides in the blood. Additionally, it has been reported to inhibit esophageal tumorigenesis in mice. These effects are likely due to the inhibition of NF-kappa B redox sensitivity.
Has anti-oxidation effect
Ellagic acid, a bioactive polyphenol found in plant foods, has antioxidant properties. It helps reduce oxidative stress and damage to DNA. Aside from antioxidant functions, ellagic acid also has anti-inflammatory, antimutagenic and anti-carcinogenic activities.
Ellagic acid is a natural phenolic compound found in a variety of fruits and vegetables. Some of its components include ellagitannins, which are found in strawberries, raspberries, pomegranates, black currents and green tea.
Ellagic acid is known to inhibit g-radiation-induced lipid peroxidation in rat liver microsomes. Moreover, ellagic acid has also been reported to have a protective effect against alcoholic liver disease. The inhibitory effects of ellagic acid on oxidative stress have been assessed using the 1,1-diphenyl-2-picrylhydrazyl radical assay.
Ellagic acid has been shown to possess anti-oxidant activity and is a good scavenger of superoxide anion. Besides, ellagic acid has been reported to exert its antioxidant properties through chelating metals.
Ellagic acid has been found to have an anti-inflammatory effect on the testes. This may help prevent sperm damage due to di (2-ethylhexyl) phthalate (DEHP).
Ellagic acid is also known to improve the organ index and enhance the male reproductive capacity in mice that were administered with monosodium glutamate-induced testicular injury. In addition, ellagic acid showed anti-tumor effects in human osteogenic sarcoma. Lastly, ellagic acid reduced inflammatory responses, inhibited DNA synthesis and produced an apoptotic effect in human osteogenic sarcoma.
Ellagic acid is an effective and potent antioxidant. It has anti-carcinogenic, anti-mutagenic, anti-inflammatory and anti-obesity properties.
May attenuate adipocyte expansion
Ellagic acid is a natural polyphenol found in some fruits and nuts. In addition to its enviable antioxidant properties, it also has been lauded for its antiproliferative effects on certain cancers. Its proponents claim that it may be a key component of a successful fat burning diet. A recent meta-analysis, conducted on a sample size of 100 participants, claims that ellagic acid attenuates the obesity juggernaut. The benefits are manifold: improved glycemia levels, reduced insulin levels and a healthier metabolic state. With the right diet and exercise regime, it’s possible to keep your waistline in check, if not trim it down to a manageable size. On a related note, a recent study suggests that ellagic acid may actually improve metabolic health by inhibiting the storage of abnormal lipids in the liver. One of the researchers even goes so far as to suggest that the liver might have the most direct effect on a person’s body weight. This might be the reason why it is a good idea to include the aforementioned supplement in one’s daily regimen.
